Recombinant Human Amyloid-like Protein 1, His (HEK293-expressed) 也稱作APLP1,在暴露于Mn 的模型中,其在額葉皮質的神經元中含量明顯上升。 Synonyms rHuAmyloid-like Protein 1, His; APLP-1; Amyloid-like Protein 1 ; 重組人淀粉樣蛋白 1,His (HEK 293表達) Species HumanSource HEK 293 Accession P51693 Gene ID 333 Molecular Weight 18-20 kDa AA Sequence GGSPGAAEAP GSAQVAGLCG RLTLHRDLRT GRWEPDPQRS RRCLRDPQRV LEYCRQMYPE LQIARVEQAT QAIPMERWCG GSRSGSCAHP HHQVVPFRCL PGEFVSEALL VPEGCRFLHQ ERMDQCESST RRHQEAQEAC SSQGLILHGS GMLLPCGSDR FRGVEYVCCP PHHHHHH Biological Activity Data is not available. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS, 1 mM EDTA, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Amyloid-like Protein 1, His (HEK293-expressed) (rHuAmyloid-like Protein 1, His) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human Amyloid-like Protein 1, His (HEK293-expressed) (rHuAmyloid-like Protein 1, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Human APLP1 gene has been mapped to the long arm of chromosome 19 in the same region containing a late-onset familial AD locus. APLP1 is a member of the amyloid precursor family. Increased APLP1 expression and revealed the presence of amyloid-β diffuse plaques. |