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Recombinant Rat VEGF165 (CHO-expressed)

英文名:
Cas號:
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貨號 規格 貨期 庫存 價格 會員價 訂購
1308132822-10 μg 0 ¥5000 請登錄
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1308132822-50 μg 0 ¥17000 請登錄
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別 名
Cas號
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分子式
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產品參數
性狀 Recombinant Rat VEGF165 (CHO-expressed)是一個有效的血管生成調節劑,并能與信號蛋白受體neuropilin1 結合。
Synonyms
rRtVEGF165; VEGF-A; VPF ; 重組大鼠血管內皮生長因子165 (CHO 表達)
Species
Rat

Source
CHO

Accession
QB5DEK7

Gene ID
83785

Molecular Weight
35-48 kDa

AA Sequence
APTTEGEQKA HEVVKFMDVY QRSYCRPIET LVDIFQEYPD EIEYIFKPSC VPLMRCAGCC NDEALECVPT SESNVTMQIM RIKPHQSQHI GEMSFLQHSR CECRPKKDRT KPENHCEPCS ERRKHLFVQD PQTCKCSCKN TDSRCKARQL ELNERTCRCD KPRR

Biological Activity
The ED50 is <4 ng/mL as measured by HUVEC cells, corresponding to a specific activity of >2.5 × 105 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Rat VEGF165 (CHO-expressed) (rRtVEGF165) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Rat VEGF165 (CHO-expressed) (rRtVEGF165) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Vascular endothelial growth factor (VEGF or VEGFA) is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the PDGF family that is characterized by the presence of eight conserved cysteine residues and a cystine knot structure[1]. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189[1][2]. VEGF165 binds the semaphorin receptor, Neuropilin1 and promotes complex formation with VEGF R2[3].
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