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| 生化科研試劑 >> 抗體產品 >> 一抗 |
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LAT Rabbit Antibody
LAT Rabbit Antibody |
| 別????名： |
LAT antibody, LAT1 antibody, pp36 antibody, Linker for activation of T-cells family member 1 antibody, p36-38 antibody |
| 貨號 |
品名 |
規格 |
包裝 |
單價 |
貨期 |
庫存 |
| 1227179033 |
LAT Rabbit Antibody |
|
100ul |
詢價 |
現貨 |
3天 |
| 提示信息：偏遠地區如新疆西藏寧夏甘肅等地可能無法運送液體，下單前請聯系客服。 |
| 性 狀： |
【產品類型】Rabbit Monoclonal IgG
【反應特異性】
【克隆 ID】Y109
【用途】WB , IHC , FC , IP
【產品性狀】
【陽性對照】
【產品濃度】
【細胞定位】
【抗原分子量】36/38 kDa |
| 質量標準： |
【產品介紹】LAT (linker f o r activation of T-cells)
is involved in the T-cell antigen recept o r (TCR)
signal transduction pathway, a n d may play an imp o r
tant role downstream in activating protein tyrosine
kinases (1). LAT is phosph o r ylated by ZAP-70/Syk
protein tyrosine kinases leading to recruitment of
multiple signaling molecules (2). It has been found
that Tyr191 a n d Tyr171 are required f o r
T-cell activation a n d Tyr132 is required f o r
the activation of PLCgamma1 a n d Ras signaling
pathways, respectively. Tyr226 a n d Tyr191 are required
f o r Vav binding, whereas Tyr171 a n d Tyr132 are
necessary f o r association a n d activation
of phosphoinositide 3-kinase activity a n d PLCgamma1 (3).WB: 1:500
IHC: 1:100
Flow Cytometry: 1:40
IP: 1:60 A. Western blot analysis on Jurkat cell lysate
using anti-LAT RabMAb (catalog #1499-1), dilution 1:500. B. Immunohistochemical analysis of paraffin-embedded
human lymph node using anti-LAT RabMAb (catalog #1499-1). |
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