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| 生化科研試劑 >> 抗體產品 >> 一抗 |
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GCDFP-15 (PIP)
Rabbit Monoclonal Antibody |
| 別????名： |
PIP antibody, GCDFP-15 antibody, GCDFP15 antibody, GPIP4 antibody, Prolactin-inducible protein antibody, gp17 antibody |
| 貨號 |
品名 |
規格 |
包裝 |
單價 |
貨期 |
庫存 |
| 1227177827 |
GCDFP-15 (PIP) |
|
100ul |
詢價 |
現貨 |
3天 |
| 提示信息：偏遠地區如新疆西藏寧夏甘肅等地可能無法運送液體，下單前請聯系客服。 |
| 性 狀： |
【反應特異性】Human
【克隆 ID】EPR1582
【用途】WB , IHC , ICC
【抗原分子量】17kDa |
| 質量標準： |
【產品介紹】Gross cystic disease fluid protein
(GCDFP-15), also called prolactin-inducible protein
(PIP), is a single polypeptide chain with a
versatile function in human reproductive and
immunological systems (1). It is unique because of its
small size (1). GCDFP-15 binds to CD4, exerts a
potent inhibition on T lymphocyte apoptosis mediated
by CD4/T-cell receptor (TCR) activation, and carries
a fibronectin-specific aspartyl protease activity (2).
Its ability to bind with other molecules like
immunoglobulin G (IgG), actin, and zinc alpha2-
glycoprotein (ZAG) shows its various biological
activities (1). GCDFP-15 is expressed in benign
and malignant human breast tumors and in normal
exocrine organs such as sweat, salivary and lacrimal
glands (1). It is up regulated by prolactin and
androgens, while it is down regulated by estrogen (1).
Due to its expression in breast cancer, GCDFP-15 is used
as a prognostic biomarker (3, 4).
Recommended Applications
WB, IHC, ICC
Applications and Recommended Dilution Factors WB: 1 : 1,000 - 10,000
IHC: 1 : 100 - 250
ICC: 1 : 100 - 250
Species Reactivity Human Products Data
Western blot analysis on (A) T47-D and (B) breast
cancer cell lysates using anti-GCDFP-15 RabMAb
(cat. # 2847-1). Immunohistochemical staining of paraffin-embedded
human breast carcinoma tissue using anti-GCDFP-15
RabMAb (cat. #2847-1). Specificity A synthetic peptide corresponding to residues in
human GCDFP-15 was used as an immunogen. |
| 貯 存： |
Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt. |
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